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  • Title: Electro-oculography in autosomal dominant vitreoretinochoroidopathy.
    Author: Han DP, Lewandowski MF.
    Journal: Arch Ophthalmol; 1992 Nov; 110(11):1563-7. PubMed ID: 1444912.
    Abstract:
    Thirteen members of a family presumed to be harboring the gene for autosomal dominant vitreoretinochoroidopathy were examined. In four affected members, electro-oculography demonstrated marked reduction of the Arden ratio (range, 1.1 to 1.5; normal, > or = 1.8), despite electroretinographic evidence of mildly affected rod function and normal cone function. These findings suggested that a diffuse disturbance of the photoreceptor-pigment epithelium complex may have been present prior to wide-spread loss of photoreceptor function in the affected members of this family. As in previously described families, the pattern of inheritance appeared consistent with autosomal dominance.
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