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  • Title: [Clinical trial of the new percutaneously active antirheumatic etofenamate. Summarising report (author's transl)].
    Author: Heindl I, Lorenz D, Sieberns S, Blumberger W.
    Journal: Arzneimittelforschung; 1977; 27(6B):1357-63. PubMed ID: 144509.
    Abstract:
    2-(2-Hydroxyethoxy)ethyl-N-(a,a,a-trifluoro-m-tolyl)anthranilate (etofenamate, Rheumon Gel), a percutaneously active antirheumatic containing etofenamate as active principle has been subjected to clinical studies in both hospitalized and out-patients in various types of rheumatic disease. These trials included double-blind studies against placebo gel, controlled comparative studies against two topical commercial products (ointmentI: combination of 2-hydroxyethyl salicylate and p-menthan-3-ol; ointment II: 3,5-dioxo-1,2-diphenyl-4-n-butylpyrazolidine) and open trials for efficacy and tolerance. Of the 760 patients taking part in the trials, 556 were treated with Rheumon Gel.
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