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  • Title: Rapid structural changes in nerve fibers evoked by electric current pulses.
    Author: Tasaki I, Byrne PM.
    Journal: Biochem Biophys Res Commun; 1992 Oct 30; 188(2):559-64. PubMed ID: 1445300.
    Abstract:
    Using the garfish olfactory nerve, the time-courses of lateral expansion (swelling) and birefringence changes in nerve fibers have been examined at the site of application of electric current pulses. The effects of various chemical agents on these non-electrical signs of rapid structural changes in the nerve fibers have been examined. These studies have shown that a pulse of outwardly-directed current through the superficial layer evokes a fast increase, followed by a slow, gradual increase, in the water-content of the nerve fibers. The full significance of these findings in studies of the process of nerve excitation is discussed.
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