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  • Title: Urea synthesis in rats fed diet containing kidney beans.
    Author: Scislowski PW, Grant G, Harris I, Pickard K, Pusztai A.
    Journal: Biochem Int; 1992 Oct; 28(1):191-7. PubMed ID: 1445392.
    Abstract:
    When rats were fed a diet containing kidney bean (Phaesolus vulgaris) urea excretion was increased 3-5 fold. Isolated liver mitochondria from rats fed the kidney bean diet produced 40% more citrulline in the presence of arginine than mitochondria isolated from control rats. Mitochondrial activities of urea cycle enzymes and N-acetylglutamate synthetase were similar in animals fed diets containing kidney bean or lactalbumin. The possible mechanisms causing acute urea production in rats fed with kidney bean are discussed.
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