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  • Title: Myo-inositol in the biosynthesis of streptomycin by Streptomyces griseus.
    Author: MAJUMDAR SK, KUTZNER HJ.
    Journal: Science; 1962 Mar 02; 135(3505):734. PubMed ID: 14468644.
    Abstract:
    When myo-inositol is present in a growing culture of Streptomyces griseus the yield of streptomycin is increased, and the amount of carbon-14-from uniformly labeled glucose-incorporated into the streptidine and streptobiosamine moieties of streptomycin is lowered by 41 percent and 21.7 percent, respectively. These results present strong indirect evidence for the participation of myo-inositol or its metabolic products in streptidine biosynthesis.
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