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  • Title: [Effect of pingchuan mixture on eosinophil cation protein and interleukin-5 in experimental guinea pigs with asthma].
    Author: Fang XM, Cao SH.
    Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi; 2003 Aug; 23(8):609-11. PubMed ID: 14503063.
    Abstract:
    OBJECTIVE: To observe the effect of Pingchuan Mixture (PCM) on plasma eosinophil cation protein (ECP), interleukin-5 in bronchial alveolar lavage fluid (BALF) and inflammatory cell count in experimental guinea pigs with asthma. METHODS: The eosinophil, neutrophil, lymphocyte count were conducted by conventional method, IL-5 was detected by ELISA and ECP determined by RIA. RESULTS: Levels of eosinophil, neutrophil, lymphocyte, ECP and IL-5 after treatment were significantly lower than those before treatment, the difference between groups treated respectively by PCM, aminophylline, dexamethasone and Dingchuan Zhike Tablet was insignificant. CONCLUSION: PCM could treat asthma by reducing the inflammatory cell count, ECP and IL-5.
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