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  • Title: Biophysical model of synaptic plasticity dynamics.
    Author: Abarbanel HD, Gibb L, Huerta R, Rabinovich MI.
    Journal: Biol Cybern; 2003 Sep; 89(3):214-26. PubMed ID: 14504940.
    Abstract:
    We discuss a biophysical model of synaptic plasticity that provides a unified view of the outcomes of synaptic modification protocols, including: (1) prescribed time courses of postsynaptic intracellular Ca(2+) release, (2) postsynaptic voltage clamping with presentation of presynaptic spike trains at various frequencies, (3) direct postsynaptic response to presynaptic spike trains at various frequencies, and (4) LTP/LTD as a response to precisely timed presynaptic and postsynaptic spikes.
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