These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: In vitro interaction of flucytosine with conventional and new antifungals against Cryptococcus neoformans clinical isolates.
    Author: Schwarz P, Dromer F, Lortholary O, Dannaoui E.
    Journal: Antimicrob Agents Chemother; 2003 Oct; 47(10):3361-4. PubMed ID: 14506059.
    Abstract:
    Combinations of flucytosine with conventional and new antifungals were evaluated in vitro against 30 clinical isolates of Cryptococcus neoformans. Synergy determined by checkerboard analysis was observed with combinations of fluconazole, itraconazole, voriconazole, amphotericin B, and caspofungin with flucytosine against 77, 60, 80, 77, and 67% of the isolates, respectively. Antagonism was never observed. Killing curves showed indifferent interactions between triazoles and flucytosine and synergy between amphotericin B and flucytosine.
    [Abstract] [Full Text] [Related] [New Search]