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  • Title: Multiple opportunistic AIDS-associated disorders strictly related to immunodeficiency levels, in a girl with congenital HIV infection.
    Author: Manfredi R, Calza L, Chiodo F.
    Journal: Int J STD AIDS; 2003 Sep; 14(9):638-9. PubMed ID: 14511504.
    Abstract:
    A 16-year-old girl with vertical HIV disease treated since birth suffered from six different AIDS-defining disorders until now. Even during the highly active antiretroviral therapy, multiple AIDS-related opportunistic infections may complicate the course of long-term congenital HIV disease, showing a strict relationship with immunological deterioration, which occurs shortly after virologic failure, due to an extensive genotypic resistance to all available antiretroviral compounds.
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