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  • Title: [Infection of Chlamydia trachomatis and apoptosis of spermatogenic cells].
    Author: Wan CC, Wang H, Hao BJ, Shang XJ, Huang YF.
    Journal: Zhonghua Nan Ke Xue; 2003 Aug; 9(5):350-1, 354. PubMed ID: 14513642.
    Abstract:
    OBJECTIVE: To evaluate the relationship between infection of Chlamydia Trachomatis(Ct) and apoptosis of spermatogenic cells. METHODS: Apoptotic spermatogenic cells were examined by Wright-Giemsa staining and the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate(dUTP)-biotin nick-end labeling(TUNEL) technique. RESULTS: Apoptosis rate of Ct infective group was significantly higher than that of normal group(P < 0.01). CONCLUSIONS: Ct infection may cause the apoptosis of spermatogenic cells, which affords an objective evidence for illustrating the mechanism of Ct-infection-induced male infertility.
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