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  • Title: [Immunologic diagnostic pulmonary diseases caused by inhaled isocyanates (author's transl)].
    Author: Wallenstein G.
    Journal: Allerg Immunol (Leipz); 1977; 23(2):120-6. PubMed ID: 145171.
    Abstract:
    Besides the strong irritative effect on the respiratory tract the isocyanates probably also have an allergenic effect. The paper gives a review of literature about immunologic in vitro- and in vivo-methods in this question. Difficulties arise especially with preparation of antigen. Isocyanates are thought to link with proteins to give antigenic conjugates. Specifity firstly depends on the isocyanate hapten.
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