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  • Title: [The evaluation of severe male infertility in the era of advanced in-vitro fertilization].
    Author: Paz G, Gamzu R, Yavetz H.
    Journal: Harefuah; 2003 Sep; 142(8-9):624-7, 644. PubMed ID: 14518168.
    Abstract:
    Male infertility has been a subject for dynamic definition during the last decade since the introduction of intracytoplasmic sperm injection (ICSI) as an acceptable and routine technique in the IVF-ART procedure. Male sterility may be defined in cases in which no spermatozoa are located in a testicular biopsy using several specimens. The extreme case (absence of all gametes precursors) is termed Sertoli cell only. This evaluation may be reinforced by detailed genetic assessments of micro-deletion in Y chromosome. Accordingly, once spermatozoa are isolated (even very few) they can fertilize an oocyte using ICSI, thereby the couple can achieve pregnancy. This shift in the definition of 'Sterility' brings about a shift in the consideration of male 'subfertility' or 'infertility'. This review explores the current 'state of the art' of male fertility evaluation with a focus on the role of an advanced andrology laboratory.
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