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  • Title: [Allogenic small intestine transplantation in the rat model with initial CsA therapy: first detection of Th2-induced immune tolerance].
    Author: Gieseler R, Peters JH, Schlemminger R.
    Journal: Langenbecks Arch Chir Suppl Kongressbd; 1998; 115(Suppl I):651-4. PubMed ID: 14518335.
    Abstract:
    It is not clear how initial therapy with CsA effects indefinite allograft acceptance after small bowel transplantation in the rat. Our study of post-transplant alterations of immune parameters within donor-type mesenteric lymph nodes suggests CsA-dependent, Th2-mediated induction of graft-specific T-cell tolerance.
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