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  • Title: Deformation of cross-linked semiflexible polymer networks.
    Author: Head DA, Levine AJ, MacKintosh FC.
    Journal: Phys Rev Lett; 2003 Sep 05; 91(10):108102. PubMed ID: 14525510.
    Abstract:
    Networks of filamentous proteins play a crucial role in cell mechanics. These cytoskeletal networks, together with various cross-linking and other associated proteins largely determine the (visco)elastic response of cells. In this Letter we study a model system of cross-linked, stiff filaments in order to explore the connection between the microstructure under strain and the macroscopic response of cytoskeletal networks. We find two distinct regimes as a function primarily of cross-link density and filament rigidity: one characterized by affine deformation and one by nonaffine deformation. We characterize the crossover between these two.
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