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  • Title: Synthesis and biological evaluation of some new substituted naphthoquinones.
    Author: Habib NS, Bekhit AA, Park JY.
    Journal: Boll Chim Farm; 2003 Jun; 142(5):232-8. PubMed ID: 14526658.
    Abstract:
    Two novel series of 1,4-naphthoquinone derivatives have been synthesized namely; N-ethoxycarbonyl-2-ethoxycarbonyloxy-3- alkyl-1,4-naphthoquinon-1-substituted phenylhydrazones 3a-f and 2-chlorocetyloxy-3-alkyl-1,4-naphthoquinone-1-substituted phenylhydrazones 4a-d. The antimicrobial activity as well as anticancer activity of these compounds have been evaluated. The acute toxicity of the active compounds was determined.
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