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  • Title: [Primary hypertrophic osteoarthropathy without cutaneous involvement (Currarino's disease)].
    Author: Ben Hamida SK, Kédadi H, Derbel F, Kchir M, Bouhaoula H, Hadj SM, Mestiri A, Zouari R, Dougui MH.
    Journal: Presse Med; 2003 Sep 27; 32(31):1455-6. PubMed ID: 14534476.
    Abstract:
    INTRODUCTION: Hypertrophic osteoarthropathy (HOA) is a syndrome associating hippocratic fingers, arthropathy and periostosis of long bones. Currarino's disease, considered at present as a clinical form of primary HOA, is characterized by the absence of pachydermia. OBSERVATION: A 24-year-old Caucasian man, consulted for a painful swelling of both ankles that had developed over the past year. Clinical examination revealed hippocratic fingers without pachydermia. The ankles were swollen. The X-rays showed periosteal apposition and an acro-osteolysis. In view of this triad: arthropathy, hippocratic fingers and periostosis, primary HOA without cutaneous involvement or Currarino's disease was diagnosed. The search for a secondary cause remained negative. Clinical improvement was obtained after 15 months with non-steroidal anti-inflammatory drugs (NSAID) and colchicine. COMMENTS: Although exceptional, primary HOA without cutaneous involvement is a genetic disease which must not be ignored.
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