These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Immunostimulating activity of synthetic bursopeptides.
    Author: Tsepelev VL, Tsepelev SL.
    Journal: Bull Exp Biol Med; 2003 Jul; 136(1):70-2. PubMed ID: 14534615.
    Abstract:
    Biologically active peptides bursopeptide-1 (Tyr-Glu-Glu) and bursopeptide-2 (Trp-Thr-Ala-Glu-Glu-Lys-Gln-Leu) from the bursa of Fabricius were isolated and synthesized. Bursopeptide-1 stimulated expression of B cell differentiation antigens in lymphocyte culture from patients with burns. Bursopeptide-2 produced a variety of effects and stimulated expression of differentiation antigens on T and B cells and natural killer cells. Bursopeptides can modulate the mechanisms of interleukin-2-mediated lymphocyte activation. Bursopeptides stimulated the immune response in mice with cyclophosphamide-induced immunodeficiency, which manifested in increased hemagglutinin and hemolysin titers and increased count of antibody-producing cells in the spleen.
    [Abstract] [Full Text] [Related] [New Search]