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  • Title: [Effects of tengcha flavonoids on scavenging oxygen free radicals and inhibiting lipid-peroxidation].
    Author: He G, Du F, Yang W, Pei G, Zhu Y.
    Journal: Zhong Yao Cai; 2003 May; 26(5):338-40. PubMed ID: 14535015.
    Abstract:
    OBJECTIVE: To study the effects of Tengcha flavonoids (TCF) on scavenging oxygen free radicals and inhibiting lipid-peroxidation. METHODS: The effects of TCF on scavenging superoxide anion radical induced by xanthine-xanthine oxidase, inhibiting lipid-peroxidation of heart, liver, brain tissue homogenate and mitochondria induced by Fe2+ -VitC, Fe2+ -H2O2, Fe-Cys were discussed by TBA spectrometric method. RESULTS: TCF could significantly inhibit the superoxide anion radical, IC50 is 14.7 mg/L, and the lipid peroxidation of liver homogenate and mitochondria induced by auto-oxidation and induced-oxidation. The inhibition exhibited concentration-dependent manner. CONCLUSION: It indicated that TCF could scavenge oxygen free radicals and was capable of prophylacticly antagonizing against the oxidative injury by superoxide anion.
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