These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: The synthesis and applications of 5-aminolevulinic acid (ALA) derivatives in photodynamic therapy and photodiagnosis.
    Author: Dabrowski Z, Kwaśny M, Kamiński J, Bełdowicz M, Lewicka L, Obukowicz B, Kaliszewski M, Pirozyńska E.
    Journal: Acta Pol Pharm; 2003; 60(3):219-24. PubMed ID: 14556493.
    Abstract:
    A route has been developed to high-purity precursors, viz., ALA esters, to be used in photodiagnosis and photodynamic therapy. Hexyl, butyl and methyl 5-aminolevulinates are similar to the ALA acid in chemical stability and efficacy in producing the appropriate photosensitizer PpIX. Tests carried out on animal models showed the method based on the esters to be the more selective.
    [Abstract] [Full Text] [Related] [New Search]