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  • Title: The effect of hyaluronan on interleukin-1 alpha-induced prostaglandin E2 production in human osteoarthritic synovial cells.
    Author: Yasui T, Akatsuka M, Tobetto K, Hayaishi M, Ando T.
    Journal: Agents Actions; 1992 Sep; 37(1-2):155-6. PubMed ID: 1456177.
    Abstract:
    An in vitro study on the effects of hyaluronan (HA) on interleukin-1 alpha-induced prostaglandin E2 (PGE2) production in human osteoarthritic synovial cells indicated that PGE2 induction was suppressed by HA in a dose- and molecular weight-dependent manner.
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