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  • Title: 4D imaging to assay complex dynamics in live specimens.
    Author: Gerlich D, Ellenberg J.
    Journal: Nat Cell Biol; 2003 Sep; Suppl():S14-9. PubMed ID: 14562846.
    Abstract:
    A full understanding of cellular dynamics is often difficult to obtain from time-lapse microscopy of single optical sections. New microscopes and image-processing software are now making it possible to rapidly record three-dimensional images over time. This four-dimensional imaging allows precise quantitative analysis and enhances visual exploration of data by allowing cellular structures to be interactively displayed from many angles. It has become a key tool for understanding the complex organization of biological processes in live specimens.
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