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  • Title: Purine derivatives of 1,2-disubstituted cyclohexane analogues of nucleosides.
    Author: Terán C, Santana L, Uriarte E, Viña D, De Clercq E.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):787-9. PubMed ID: 14565279.
    Abstract:
    Starting from (+/-)-cis-2-hydroxymethylcyclohexylamine, a series of cyclohexane-derived cis-1,2-disubstituted carbonucleoside analogues with a 6- or 2,6-purine or 8-azapurine base were synthesized. The antiviral and antitumoral in vitro effects of the new compounds were evaluated.
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