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  • Title: 2'-Deoxy-2'-C-trifluoromethyl beta-D-ribonucleoside analogues: synthesis and antiviral evaluations.
    Author: Jeannot F, Gosselin G, Mathé C.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):857-9. PubMed ID: 14565296.
    Abstract:
    Hitherto unknown 2'-deoxy-2'-C-trifluoromethyl-beta-D-ribonucleoside derivatives bearing the five naturally occurring nucleic acid bases have been synthesized. The compounds were tested for their activity against HIV, HBV and several RNA viruses, but they did not show significant antiviral effect.
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