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Title: Synthesis, stability, and biological evaluation of 1,3-dihydrobenzo[c]furan analogue of d4T and its SATE pronucleotide. Author: Len C, Selouane A, Postel D, Villa P, Aubertin AM, Egron D, Gosselin G, Périgaud C. Journal: Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):943-5. PubMed ID: 14565317. Abstract: The anti-HIV activity and stability studies of 1,3-dihydrobenzo[c]furan analogue of d4T are reported. The corresponding mononucleoside phosphotriester derivative bearing a S-pivaloyl-2-thioethyl (tBuSATE) group, as biolabile phosphate protection, is also studied.[Abstract] [Full Text] [Related] [New Search]