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Title: Ribo-, xylo-, and arabino-configured adenine-based nucleoside phosphonates: synthesis of monomers for solid-phase oligonucleotide assembly. Author: Páv O, Budesínský M, Rosenberg I. Journal: Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1053-6. PubMed ID: 14565342. Abstract: Adenine-based, regioisomeric nucleoside phosphonates with ribo, xylo and arabino configuration were synthesized in the protected form suitable for the phosphotriester-like, solid-phase synthesis of oligonucleotides. Phosphonate moiety was protected by 4-methoxy-1-oxido-2-picolyl group and the furanose hydroxyl by the dimethoxytrityl group.[Abstract] [Full Text] [Related] [New Search]