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  • Title: Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with multisubstrate analogue inhibitor with 2,6-diaminopurine aglycone.
    Author: Koellner G, Stroh A, Raszewski G, Holý A, Bzowska A.
    Journal: Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1699-702. PubMed ID: 14565499.
    Abstract:
    The crystal structure at 2.05 A resolution of calf spleen PNP complexed with stoichiometric concentration of acyclic nucleoside phosphonate inhibitor, 2,6-diamino-(S)-9-[2-(phosphonomethoxy)propyl]purine, in a new space group P2(1)2(1)2(1) which contains two full trimers in the asymmetric crystal unit is described.
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