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  • Title: Hemoglobin C--G-Georgia double heterozygosity: a case report.
    Author: Reynolds S, Miller C, King R, Lazarchick J.
    Journal: Ann Clin Lab Sci; 1992; 22(6):414-6. PubMed ID: 1456731.
    Abstract:
    A 12-month-old black female with an unremarkable past medical history was admitted to the hospital with respiratory distress and fever without identified sepsis. Despite mechanical ventilation, the patient died as a result of respiratory insufficiency secondary to severe necrotizing bronchitis and bronchiolitis with pneumonia. Electrophoretic and biochemical analyses of the patient's hemoglobin showed the patient to be a double heterozygote for hemoglobin C (a beta chain variant) and hemoglobin G-Georgia (an alpha chain variant). This is the first report of this combination of hemoglobin variants.
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