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Title: [European multicenter cross-sectional study on exposure to low doses of benzene]. Author: Merlo F, Bertazzi PA, Bolognesi C, Colombi A, Fustinoni S, Buratti M, Farmer P, Garte S, Levy L, Pesatori AC, Popov T, Taioli E, Valerio F, Consonni D. Journal: G Ital Med Lav Ergon; 2003; 25(3):296-7. PubMed ID: 14582242. Abstract: A cross-sectional multicenter european study has been carried out to evacuate the relations between exposure to low level of benzene and biological markers of internal dose (t,t-MA, S-PMA) and early biological effect (DNA-SSB). The research has shown significantly increased levels (adjusted for smoking habits) of the urinary excretion of t,t-MA, S-PMA and DNA-SSB in petrochemical workers (mean benzene level = 5,694 micrograms/m3) but not in filling station attendants, traffic police officers, and bus drivers compared to referent workers. Dose-response relations were detected between benzene air levels, t,t-MA, S-PMA and DNA-SSB in petrochemical workers, with significantly increased levels of DNA-SSB detected for benzene exposure levels in the range 391-1,800 micrograms/m3 (0.12-0.58 ppm).[Abstract] [Full Text] [Related] [New Search]