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  • Title: Pulmonary adenocarcinoma with osteoblastic bone metastases in a cat.
    Author: Nakanishi M, Kuwamura M, Ueno M, Yasuda K, Yamate J, Shimada T.
    Journal: J Small Anim Pract; 2003 Oct; 44(10):464-6. PubMed ID: 14582662.
    Abstract:
    A 12-year-old male cat with depression and dyspnoea was presented for investigation. Radiography and computed tomography revealed hydrothorax and solid masses involving the sternum, ribs and thoracic vertebrae. The cat died two days after first presentation, and postmortem examination revealed lung masses and proliferative bony lesions. Histologically, a neoplastic proliferation of epithelial cells was seen in the lungs, with a large amount of collagen and deposits of cholesterin. The bone lesions were also composed of neoplastic epithelial cells and abundant calcified osteoid, without atypia. A diagnosis of pulmonary adenocarcinoma with osteoblastic bone metastases was made. This is the first reported case of osteoblastic metastases in the cat.
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