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  • Title: Clinically silent Paget disease of male nipple.
    Author: Piekarski J, Kubiak R, Jeziorski A.
    Journal: J Exp Clin Cancer Res; 2003 Sep; 22(3):495-6. PubMed ID: 14582713.
    Abstract:
    Male breast cancer constitutes less than 1% of all breast cancer cases. Special types, such as Paget disease of the breast, are extremely rare. To our knowledge there are less than 50 cases of Paget disease of male breast described in world medical literature. Authors present pathologically proven but clinically silent case of Paget disease of the nipple in an 86-year old male with breast cancer. Literature data suggest that the prognosis of male Paget cancer is worse than in "ordinary" male breast cancer. Therefore, the histologic diagnosis of Paget disease, even in an asymptomatic male patient, may have negative prognostic value.
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