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  • Title: Linezolid-associated toxic optic neuropathy: a report of 2 cases.
    Author: Lee E, Burger S, Shah J, Melton C, Mullen M, Warren F, Press R.
    Journal: Clin Infect Dis; 2003 Nov 15; 37(10):1389-91. PubMed ID: 14583875.
    Abstract:
    We describe 2 cases in which the prolonged use of linezolid to treat complicated methicillin-resistant Staphylococcus aureus infections was followed by acutely developed blurred vision and progressive loss of vision and color perception during the ensuing few weeks. Both patients received a diagnosis of toxic optic neuropathy, and linezolid therapy was stopped. The patients experienced an initial rapid partial improvement and a subsequent gradual, almost complete, recovery over many months.
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