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  • Title: [Randomized trials in the prevention of recurrent calcium oxalate stones].
    Author: Presne C, Monge M, Bataille P, el Esper N, Choukroun G, Fournier A.
    Journal: Nephrologie; 2003; 24(6):303-7. PubMed ID: 14584297.
    Abstract:
    Kidney stone, with or without lumbar pain, is a major health care problem because of its prevalence and cost for both the patient and the society. Although, surgical procedures are well known, medical treatment and recurrences prophylaxis are uncodified. Fifteen stone recurrence prevention studies have been reviewed, evaluating dietary intake and drugs. The most important factor is a daily diuresis of at least 2 liters. Calcium intake shouldn't be restricted, whereas oxalate, sodium, and protein intakes have to be limited. Hyper and normocalciuretic kidney stone formers improve their outcome with thiazide or indapamide treatment. Hyperuricosuria justifies allopurinol. Potassium citrate (without sodium) may decrease recurrence risk, even in patients without hypocitraturia.
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