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  • Title: Ciprofloxacin-resistant Escherichia coli from bacteraemias in England; increasingly prevalent and mostly from men.
    Author: Livermore DM, Nichols T, Lamagni TL, Potz N, Reynolds R, Duckworth G.
    Journal: J Antimicrob Chemother; 2003 Dec; 52(6):1040-2. PubMed ID: 14585850.
    Abstract:
    OBJECTIVES: To assess ciprofloxacin resistance among Escherichia coli isolates from bacteraemia patients in England in relation to age, sex and Region. METHODS: Routine susceptibility data for bacteraemia isolates were collected from over 90% of hospitals in England. RESULTS: During 1995-2001, the prevalence of ciprofloxacin resistance trebled, from 2.1% to 6.5%. Isolates from men were more frequently resistant than those from women, possibly because infections in men more often involve nosocomial strains. Resistance was rare (<1.5%) in isolates from patients aged <1 year; among older patients, resistance was unrelated to age in isolates from women, but peaked in the 15-44 age group for men. CONCLUSIONS: The prevalence of ciprofloxacin resistance in E. coli from bacteraemia is strongly associated with sex and, to a lesser extent, age.
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