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  • Title: Outcome of macular hole surgery.
    Author: Khokhar AR, Faiz-ur-Rab K, Akhtar HU.
    Journal: J Coll Physicians Surg Pak; 2003 Oct; 13(10):569-72. PubMed ID: 14588170.
    Abstract:
    OBJECTIVE: To document the outcome of macular hole surgery in terms of improvement of visual acuity and the duration of closure of macular hole. DESIGN: Interventional quasi experimental study. PLACE AND DURATION OF STUDY: Ophthalmology Department, Civil Hospital, Karachi. SUBJECTS AND METHODS: Twenty-four eyes of 22 patients with macular hole underwent surgical repair. Vitrectomy with maculorrhexis (internal limiting membrane peeling) and fluid-gas exchange followed by prone positioning for one to two weeks was carried out. Postoperative follow-up was done for one year. Main outcome measures were visual acuity, closure of macular hole and ocular complications. Data was analyzed by using SPSS Version 10. Non-parametric sign test with chi-square statistic was used to compare the pre-operative and postoperative outcome. RESULTS: The macular hole was successfully closed in 17 eyes that revealed high statistical significance regarding improvement in visual acuity. Earlier, significant improvement figured in 17/24 cases was observed at three-month post-operative examination (p<0.0001). An insignificant success figured in 8/24 due to postoperative complications at six-month follow-up. Visual acuity improved upto two or more lines in 17 eyes at one-year follow-up. Twelve cases developed cataract, 7 developed increased intra-ocular pressure (transient), one had glaucoma and one retinal detachment. CONCLUSION: Vitrectomy with maculorrhexis (internal limiting membrane peeling) and fluid-gas exchange can successfully close macular holes and improve vision.
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