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  • Title: Cytogenetic analysis of spontaneous abortions with direct analysis of chorionic villi.
    Author: Gardó S, Bajnóczky K.
    Journal: Eur J Obstet Gynecol Reprod Biol; 1992 Nov 19; 47(2):117-20. PubMed ID: 1459324.
    Abstract:
    A total of 224 cases of spontaneous abortions were studied by analysing chromosomes directly from chorionic villi. Abnormal karyotypes were found in 51.3% of the investigated cases. Among the chromosome abnormalities the most frequent were the trisomies (55.7%), followed by polyploidy (23.5%), monosomy X (15.6%) and structural anomalies (5.2%). The rapid and relatively simple method is suitable for studying the causes of spontaneous abortions, and this information may be helpful also for genetic counselling.
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