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  • Title: [The results of conservative treatment of oxalate urolithiasis in children].
    Author: Rogowska-Kalisz A, Tkaczyk M, Bilińska W, Nowicki M.
    Journal: Pol Merkur Lekarski; 2003 Jul; 15(85):51-4. PubMed ID: 14593960.
    Abstract:
    UNLABELLED: Hyperoxaluria is defined as urinary oxalate excretion exceeding 0.45 mmol/1.73 m2/day and accounts for 15% of recurrent urolithiasis. There have been only a few reports on the prevalence and treatment of oxalate urolithiasis in children. THE AIM: Of the study was to assess the efficacy and safety of the protocol of intensive and combined treatment of hyperoxaluria in children. MATERIAL AND METHODS: Seventeen children at the mean age of 11.5 +/- 4.5 years with positive history of urolithiasis and diagnosis of hyperoxaluria were studied. In this group hyperoxaluria was an isolated defect in 9 of 17 children, but in 3/17 it was accompanied by hyperuricosuria, in 5/17 by hypomagnesuria and in 1 case by hypercalciuria. During the 12-month period the children were intensively hydrated and received a low-oxalate diet and supplemental therapy with vitamin B6, magnesium, citrates and lactic acid bacteria preparations. RESULTS: In all but one child oxaluria decreased below 0.45 mmol/1.73 m2/day (decrease by 45%). No new stone formation was seen during the observation period. In all patients abdominal pain and haematuria subsided. CONCLUSIONS: We conclude that the intensive, complex, conservative treatment of hyperoxaluria in children is effective and safe. It allows to decrease hyperoxaluria and prevent the recurrence of urolithiasis.
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