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  • Title: New guaianolides from leaves and stems of Chrysanthemum boreale.
    Author: Lee JR, Yang MS, Lee J, Hwang SW, Kho YH, Park KH.
    Journal: Planta Med; 2003 Sep; 69(9):880-2. PubMed ID: 14598224.
    Abstract:
    The 8-acetoxy-2-methoxy-10-hydroxy-3,11(13)-guaiaden-12,6-olide 1 and 8,10-diacetoxy-2-methoxy-3,11(13)-guaiadiene-12,6-olide 2 were isolated from Chrysanthemum boreale Makino. Compound 1 inhibited the etoposide-induced apoptosis in U 937 cells with an IC50 value 8.6 microg/mL.
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