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  • Title: The familial relation of personality disorders (DSM-II-R) to unipolar major depression.
    Author: Maier W, Lichtermann D, Minges J, Heun R.
    Journal: J Affect Disord; 1992 Nov; 26(3):151-6. PubMed ID: 1460164.
    Abstract:
    Four hundred and fifty directly interviewed relatives of probands with non-psychotic unipolar major depression and 320 directly interviewed relatives of controls were compared by the prevalences of personality disorders (P.D.) as defined by DSM-III-R, in relation to presence or absence of the relatives' affective disorder. Overall, there was only a trend for an increased risk for P.D. in relatives of depressed patients. However, P.D. and unipolar major depression co-occurred more frequently in relatives than expected by chance. It is suggested that this association is mainly due to non-familial factors. Compared with other P.D., the relationship of borderline P.D. to major depression was not substantially stronger.
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