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  • Title: Noninvasive ventilatory strategies in the management of a newborn infant and three children with congenital central hypoventilation syndrome.
    Author: Tibballs J, Henning RD.
    Journal: Pediatr Pulmonol; 2003 Dec; 36(6):544-8. PubMed ID: 14618648.
    Abstract:
    Four children with congenital central hypoventilation syndrome (CCHS) treated with noninvasive techniques of ventilation are presented. Two infants (one in the newborn period) were treated with nasal mask bilevel positive airway pressure (BiPAP), and then both were transitioned to negative pressure chamber ventilation at several years of age because of possible midface hypoplasia. Tracheostomies were not performed. Two older children were transitioned from mechanical ventilation via tracheostomy to nasal mask BiPAP, and then in one case to negative pressure chamber ventilation, and in the other to phrenic nerve pacing. Their tracheostomies were removed.
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