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  • Title: Association of vasa previa at delivery with a history of second-trimester placenta previa.
    Author: Francois K, Mayer S, Harris C, Perlow JH.
    Journal: J Reprod Med; 2003 Oct; 48(10):771-4. PubMed ID: 14619643.
    Abstract:
    OBJECTIVE: To evaluate whether vasa previa at delivery is associated with a history of second-trimester placenta previa. STUDY DESIGN: Retrospective, case-control study of all vasa previa cases at Good Samaritan Regional Medical Center from January 1, 1991, to May 1, 2001. Cases were identified by ICD-9 codes and confirmed by chart review. Each case was matched in a 1:4 ratio with controls based upon normal placentation at delivery, ultrasound documentation of midtrimester placental location, maternal parity and gestational age at delivery. RESULTS: During the study period, 13 cases of vasa previa were identified. Nine cases (9/13, 69.2%) of vasa previa at delivery had a second-trimester placenta previa as documented by midtrimester ultrasonography, whereas 2 controls (2/52, 3.8%) had a second-trimester placenta previa (P < .000001, OR = 56.3, 95% CI = 8.9-354.1). CONCLUSION: There is a highly significant association between vasa previa at delivery and a history of second-trimester placenta previa.
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