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  • Title: New oxazole-based peptidomimetics: useful building blocks for the synthesis of orthogonally protected macrocyclic scaffolds.
    Author: Mann E, Kessler H.
    Journal: Org Lett; 2003 Nov 27; 5(24):4567-70. PubMed ID: 14627385.
    Abstract:
    [structure: see text] The synthesis of a new family of densely functionalized oxazole-containing amino acids is described. These building blocks were employed for preparing macrocycles containing Lys and Glu residues by a combination of solid- and solution-phase synthesis. The resulting structures are presented as orthogonally protected scaffolds for supramolecular chemistry.
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