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Title: MoMLV reverse transcriptase regulates its own expression. Author: Bradley C, Craigie R. Journal: Cell; 2003 Oct 31; 115(3):250-1. PubMed ID: 14636552. Abstract: A precise ratio of Gag:Gag-Pol expression is required for assembly of infectious retroviral virions. In this issue of Cell, Orlova et al. show that MoMLV reverse transcriptase binds the translation release factor eRF1, and that this interaction promotes translation readthrough to make Gag-Pol.[Abstract] [Full Text] [Related] [New Search]