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  • Title: Altered global shape discrimination in deprivation amblyopia.
    Author: Jeffrey BG, Wang YZ, Birch EE.
    Journal: Vision Res; 2004 Jan; 44(2):167-77. PubMed ID: 14637366.
    Abstract:
    To assess the effect of deprivation amblyopia on global shape discrimination, sensitivity to radial deformation of circular patterns was assessed in patients treated for congenital (N=7) or developmental (N=1) cataracts. Elevation in radial deformation threshold was dependent on circular contour frequency and the depth of amblyopia. Analysis of thresholds expressed as Weber fractions indicated a shift in global integration to a larger scale. In a pedestal experiment, equivalent intrinsic noise increased in proportion to the depth of amblyopia. The results suggest neural undersampling in V1 and/or higher visual cortical areas in deprivation amblyopia and a possible role for neural disarray.
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