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  • Title: Acanthamoeba keratitis as a complication of orthokeratology.
    Author: Xuguang S, Lin C, Yan Z, Zhiqun W, Ran L, Shiyun L, Xiuying J.
    Journal: Am J Ophthalmol; 2003 Dec; 136(6):1159-61. PubMed ID: 14644232.
    Abstract:
    PURPOSE: To present four cases of Acanthamoeba keratitis as a complication of orthokeratology. DESIGN: Observational case report. METHODS: Four patients with Acanthamoeba keratitis had histories of overnight orthokeratology lens wear of 6 months to 2 years. RESULTS: Three cases were diagnosed with Acanthamoeba keratitis by corneal scraping and one by confocal microscopy examination. The patients were treated with chlorhexidine, metronidazole, and neomycin sulfate, resulting in a rapid resolution of ocular inflammation. CONCLUSION: Overnight wear of orthokeratology lenses may induce Acanthamoeba keratitis.
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