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  • Title: [Clinical value comparison between chemiluminescent immunoassay and immunoradiometric assay in detecting TSH in serum].
    Author: Yu JY, Lin Y.
    Journal: Hunan Yi Ke Da Xue Xue Bao; 2003 Jun; 28(3):275-7. PubMed ID: 14653089.
    Abstract:
    OBJECTIVE: To compare the clinical value between chemiluminescent immunoassay (CLIA) and immunoradiometric assay (IRMA) in detecting TSH in patients with hyperthyroidism and hypothyroidism. METHODS: The TSH levels in serums were detected by CLIA and IRMA in 112 normal persons, 120 hyperthyroidism patients and 58 hypothyroidism patients. RESULTS: CLIA was significantly correlated with IRMA (r = 0.98, P < 0.01). CLIA had higher coincidence rate than IRMA in the diagnosis of hyperthyroidism and hypothyroidism, and CLIA was more accurate and repetitive than IRMA. CONCLUSION: CLIA is more valuable than IRMA in diagnosing both hyperthyroidism and hypothyroidism.
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