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  • Title: [MR imaging of bone metastasis].
    Author: Koyama M, Kuroda Y, Sano A, Nishizawa S, Murakami M, Miyamoto S, Ando K, Maruta T, Ishikura S, Matsumoto S.
    Journal: Nihon Igaku Hoshasen Gakkai Zasshi; 1992 Nov 25; 52(11):1550-8. PubMed ID: 1465336.
    Abstract:
    One hundred and three patients with known malignancy and suspected bone metastasis underwent magnetic resonance imaging. In 93%, the metastatic lesions, detected both on plain films and radionuclide bone scans, showed decreased signal intensity on T1-weighted images and increased signal intensity on T2-weighted images. All lesions, except one lesion showing much blastic change on plain films, showed contrast enhancement with Gd-DTPA administration. Although further investigation is needed, a correlation between the type of primary malignancy and the signal intensity of the metastatic lesion is suggested. Among 312 metastatic lesions detected by MR imaging, 272 lesions (87%) and 134 lesions (40%) were also detected by radionuclide bone scans and plain films, respectively. In five cases, MR imaging clearly revealed the lesion compressing the spinal cord, which helped us formulate a therapeutic plan. We conclude that MR imaging is the most sensitive examination for detecting bone metastasis and is necessary for planning treatment.
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