These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Variations in the effect of clonidine on arterial pressure in rats in the presence of various anesthetics].
    Author: Bousquet P, Gaertner M, Feldman J, Bloch R.
    Journal: C R Seances Soc Biol Fil; 1977; 171(5):1129-33. PubMed ID: 146557.
    Abstract:
    The central hypotensive agent, clonidine (30 microgram/kg i.v.) has been injected in normotensive rats anesthetized with various agents. This dose of clonidine elicits usually a biphasic blood pressure response, i.e. a transient increase due to peripheral vasoconstriction, followed by a long lasting decrease. This has been observed in the animals anesthetized with pentobarbitone as well as with urethane. The hypotensive effect is abolished during chloralose, ketamine or Alfatésine anesthesia. These data emphasize that some anesthetics mays particularly modify the effects of centrally acting cardiovascular drugs.
    [Abstract] [Full Text] [Related] [New Search]