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  • Title: Cellular immunity in pregnancy: blast transformation and rosette formation of maternal T and B lymphocytes: A cross-section analysis.
    Author: Birkeland SA, Kristoffersen K.
    Journal: Clin Exp Immunol; 1977 Dec; 30(3):408-12. PubMed ID: 146581.
    Abstract:
    In vitro tests of cellular immune responses, using lymphocyte transformation tests and rosette tests for T and B lymphocytes, were studied in a cross-section analysis of a total of fifty-five patients in six groups (non-pregnant, 2--3 months pregnant, 4--5 months pregnant, 6--7 months pregnant, at parturition and 3 months after parturition). No pregnancy-related changes were found in the numbers of T, B or null cells, nor changes in PHA, PWM or MLC responses, but a significant reversible depression of the PPD response was found in the second half of pregnancy.
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