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  • Title: Nasal glioma and encephalocele: diagnosis and management.
    Author: Rahbar R, Resto VA, Robson CD, Perez-Atayde AR, Goumnerova LC, McGill TJ, Healy GB.
    Journal: Laryngoscope; 2003 Dec; 113(12):2069-77. PubMed ID: 14660905.
    Abstract:
    OBJECTIVE: To review the biology of nasal glioma and encephalocele and to present an algorithm for preoperative evaluation and surgical management. DESIGN: Retrospective review and analysis. SETTING: Tertiary care medical center: 1970 to 2002. PATIENT: Sixteen patients with glioma (n = 10) and encephalocele (n = 6). OUTCOME: Age at the time of presentation, sex, signs and symptoms, imaging findings, surgical approach, pathology, complications, rate of recurrence, and follow-up were recorded. RESULTS: Ten patients presented with nasal glioma with a mean age of 9 months. All patients underwent surgical excision. No complication was encountered with a mean follow-up of 3.5 years. Six patients presented with encephaloceles with a mean age of 15.5 months. All patients underwent surgical excision. Complications included cerebrospinal fluid leak (n = 1) and epiphora (n = 1). Follow-up was 1 to 14 years (mean, 4 years). CONCLUSION: Nasal glioma and encephalocele are rare, benign, congenital lesions with a potential for intracranial extension. Evaluation should include a complete rhinologic and neurologic examination. Preoperative imaging with a thin-cut axial and coronal computed tomography scan and/or multiplanar magnetic resonance imaging is essential. Surgical intervention should be performed soon after diagnosis to alleviate the increased risk of meningitis. A frontal craniotomy approach is recommended if intracranial extension is identified based on preoperative evaluation, followed by an extracranial resection. If there is no evidence of intracranial extension, a conservative extracranial approach is recommended.
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