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  • Title: Acute electroretinographic changes during sildenafil (Viagra) treatment for erectile dysfunction.
    Author: Balacco Gabrieli C, Regine F, Vingolo EM, Rispoli E, Isidori A.
    Journal: Doc Ophthalmol; 2003 Sep; 107(2):111-4. PubMed ID: 14661900.
    Abstract:
    The authors describe their findings on 12 subjects who were treated with 50 mg of sildenafil (Viagra) and underwent ERG measurements prior to and 1 hour after ingestion. The Naka-Rushton equation was used to describe the b-wave luminance-response function of the scotopic ERG. Statistically significant differences were noted in the Vmax and K values. Sildenafil ingestion resulted in an increase in Vmax (higher rod response to light stimuli) and a decrease in K (higher sensitivity).
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